Jdrf canadian clinical trial

Imagine being able to avoid dangerous blood sugar highs and lows without monitoring your blood glucose or taking insulin injections. The encapsulation device holds pancreatic progenitor cells that are produced by a proprietary method from a stem cell line, and together the combination product candidate is intended to address the current limitations of islet transplantation. The device will be implanted under the skin of the patient in an outpatient surgical procedure.

The cells are then expected to develop into mature pancreatic endocrine cells that will secrete insulin and other factors, thereby regulating blood sugar levels. If effective, this therapy could reduce or even eliminate the need for insulin injections. James Shapiro. Shapiro is renowned for determining how to administer human islets, resulting in insulin independence for many diabetes patients. We do not yet know what triggers this autoimmune process, but the result is the destruction of beta cells.

The underlying autoimmune process that causes type 1 diabetes distinguishes it from the more-common type 2 diabetes. This autoimmune process also means type 1 diabetes shares common pathologic pathways with diseases such as multiple sclerosis, autoimmune thyroid disease, and celiac disease. As type 1 diabetes develops early in life, including under age 5, people with type 1 diabetes are at-risk for developing complications as young as their mids or early 30s.

JDRF is the leading global non-profit organization focused on type 1 diabetes research. If certain medical tests, such as an X-ray scan, for example, make you uncomfortable, ask in advance if those or other procedures will be part of the clinical trial.

Many clinical trial participants report a positive experience. Talking to someone who has participated in the past can help you learn what to expect. Reality: Clinical trials may provide an opportunity to access new medical advances. Participants also receive free, quality care at top facilities throughout the trial.

And many participants appreciate being able to help move research forward. Reality: Clinical trial participants can leave a trial for any reason, at any time. Some trials may require just a few site visits without any overnight stays, while others may be more time-consuming.